The Recombinant Glyt2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C130864) against Glyt2. This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Mouse brain. The target is localized to the Cell membrane {ECO:0000269|PubMed:16751771, ECO:0000269|PubMed:31370103}; Multi-pass membrane protein {ECO:0000255}.