The Recombinant GSDMD Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C333259) against GSDMD. GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Jurkat. The target is localized to the cytosol, NLRP3 inflammasome complex, extracellular region or secreted, extracellular region, extracellular space, nucleus, nucleoplasm, Plasma Membrane, other locations: ficolin-1-rich granule lumen, specific granule lumen, tertiary granule lumen.
