Human BCL-W/BCL2L2 Recombinant Protein (RPES3400)
- SKU:
- RPES3400
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Death
Frequently bought together:
Description
system_update_altDatasheet
Human BCL-W/BCL2L2 Recombinant Protein
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
| Product Name: | Human BCL-W/BCL2L2 Recombinant Protein (RPES3400) |
| Product Code: | RPES3400 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Bcl-2-Like Protein 2, Bcl2-L-2, Apoptosis Regulator Bcl-W, BCL2L2, BCLW, KIAA0271 |
| Accession: | Q92843 |
| Sequence: | Ala2-Thr172 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human B Cell Lymphoma/Leukemia w is produced by our E.coli expression system and the target gene encoding Ala2-Thr172 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 19.9 kDa |
| AP Mol Mass: | 18 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 25mM HEPES, 100mM KCl, 20% Glycerol, pH 7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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