The protein CRADD (CRADD) is found in most tissues, with especially high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. The CRADD domain consists of one CARD domain that interacts with caspase-2 and one death domain that binds RIP protein. CRADD binds to apoptotic adaptor molecules for caspase-2 and FASL/TNF receptor-interacting protein RIP. CCRADD causes cell death in a variety of tissues. Deficiencies of CRADD can lead to mental retardation. Human CRADD/RAIDD Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human CRADD/RAIDD Recombinant Protein (RPES3942)
Product Code:
RPES3942
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Death Domain-Containing Protein CRADD, Caspase and RIP Adapter with Death Domain, RIP-Associated Protein with A Death Domain, CRADD, RAIDD
Accession:
P78560
Sequence:
Met1-Glu199
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human CRADD is produced by our E.coli expression system and the target gene encoding Met1-Glu199 is expressed.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
23 kDa
AP Mol Mass:
21 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
