Human GADD45A/DDIT Recombinant Protein (RPES2363)
- SKU:
- RPES2363
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Cycle
Frequently bought together:
Description
system_update_altDatasheet
Human GADD45A/DDIT Recombinant Protein
Growth Arrest and DNA Damage-Inducible Protein GADD45 ? (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation; X-rays; growth arrest and alkylating agents; of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14; GADD45GIP1; PCNA. In T-cells; GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes; stimulating DNA excision repair in vitro and inhibits entry of cells into S phase.
| Product Name: | Human GADD45A/DDIT Recombinant Protein (RPES2363) |
| Product Code: | RPES2363 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha, DNA Damage-Inducible Transcript 1 Protein, DDIT-1, GADD45A, DDIT1, GADD45 |
| Accession: | P24522 |
| Sequence: | Met1-Arg165 |
| Fusion tag: | N-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human GADD45A alpha is produced by our E.coli expression system and the target gene encoding Met1-Arg165 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 20.5 kDa |
| AP Mol Mass: | 18 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
