The Recombinant Integrin αV Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110904) against Integrin αV. The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by IHC analysis of Human bladder cancer. The target is localized to the Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.