The Recombinant Integrin beta 5 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C733360) against Integrin beta 5. Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses.In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Rat and Hamster samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of C6, CHO-K1, Hela. The target is localized to the membrane.
Product Name:
Recombinant Integrin beta 5 Monoclonal Antibody
SKU:
AGEL8665
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
beta 5, FLJ26658, integrin, Integrin beta-5, Integrin subunit beta 5, ITB5, Itgb5, Testis secretory sperm-binding protein Li 217p
![Anti-Integrin beta 5 [R04-0G6] Monoclonal Antibody (AGMB02195)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/273484/679726/anti-integrin-beta-5-r04-0g6-monoclonal-antibody-agmb02195__03785.1773039856.jpg?c=2 "Anti-Integrin beta 5 [R04-0G6] Monoclonal Antibody (AGMB02195)")
