The Recombinant ISG20 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321530) against ISG20. Interferon-stimulated 20 kDa protein (ISG20) is an exoribonuclease that functions as part of the host innate immune response to RNA-based viruses. Indeed, expression of ISG20 can be induced by type-I and type-II interferons following cellular exposure to RNA-based viruses. Mechanistically, ISG20 localizes to the nucleolus and is believed to inhibit the replication of RNA-based viruses, in part, by employing 3'-5' exonuclease activity toward viral RNAs. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of Ramos. The target is localized to the cytoplasm, nucleus.
Product Name:
Recombinant ISG20 Monoclonal Antibody
SKU:
AGEL6835
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
CD25, HEM, HEM45, ISG, ISG20
Reactivity:
Human
Immunogen:
A synthetic peptide of human ISG20
Applications:
WBIHC-P
Clonality:
Recombinant Monoclonal
Clone No:
C321530
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
ISG20
Conjugation:
Unconjugated
Observed MW:
20 kDa
Calculated MW:
20 kDa
Recommended Dilution:
WB 1:1000-5000; IHC-P 1:50-100
UniProt:
Q96AZ6
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
