The Recombinant JMJD2D Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331639) against JMJD2D. JMJD2D (KDM4D) is a histone demethylase located in the nucleus that specifically demethylates Lysine 9 of Histone H3, thereby playing a central role in the histone code. JMJD2D (KDM4D) demethylates both di- and trimethylated histone H3 Lys 9, while it has no activity on monomethylated residues. The demethylation reaction of the Lys residue generates formaldehyde and succinate as a by product. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of HeLa,?PC-3. The target is localized to the nucleus.
Product Name:
Recombinant JMJD2D Monoclonal Antibody
SKU:
AGEL6944
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
JHD3D, JHDM3D, JmjC domain-containing histone demethylation protein 3D, JMJD2D, Jumonji domain-containing protein 2D, KDM4D, Lysine-specific demethylase 4D
Reactivity:
Human
Immunogen:
Peptide. This information is proprietary to PTMab.
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C331639
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
JMJD2D
Conjugation:
Unconjugated
Observed MW:
65 kDa
Calculated MW:
59 kDa
Recommended Dilution:
WB 1:1000
UniProt:
Q6B0I6
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
