The Recombinant KDM2A Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111316) against KDM2A. Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and Trimethylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF and IP applications. It has been validated by WB analysis of Jurkat and IF analysis of HeLa. The target is localized to the nucleus.
Product Name:
Recombinant KDM2A Monoclonal Antibody
SKU:
AGEL6621
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
[Histone-H3]-lysine-36 demethylase 1A, CXXC, CXXC-type zinc finger protein 8, CXXC8, F box / LRR repeat protein 11, F box and leucine rich repeat protein 11, F box protein FBL7, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, FBL, FBL11, FBL7, FBXL, FBXL11, JHDM1A, JmjC domain-containing histone demethylation protein 1A, Jumonji C domain containing histone demethylase 1A, KDM2A, KIAA, KIAA1004, LILINA, Lysine (K) specific demethylase 2A, lysine demethylase 2A, Lysine-specific demethylase 2A
Reactivity:
Human, Mouse, Rat
Immunogen:
A synthetic peptide of human FBXL11
Applications:
WBIHC-PICC/IFIP
Clonality:
Recombinant Monoclonal
Clone No:
C111316
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
KDM2A
Conjugation:
Unconjugated
Observed MW:
133 kDa
Calculated MW:
133 kDa
Recommended Dilution:
WB 1:1000; IHC-P 1:100-200; ICC/IF 1:500-1000; IP 1:50-100
UniProt:
Q9Y2K7
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.