The Recombinant MAGEA1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C311217) against MAGEA1. May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC and IF applications. It has been validated by WB analysis of A431, IHC analysis of Human testis and IF analysis of HeLa. The target is localized to the cytoplasm, nucleus.
Product Name:
Recombinant MAGEA1 Monoclonal Antibody
SKU:
AGEL6522
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Antigen MZ2 E, Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, CT1.1, MAGA1, MAGE, MAGE 1 antigen, MAGE-1 antigen, MAGE1, MAGE1A, MAGEA, MAGEA1, Melanoma antigen 1, Melanoma antigen family A 1, Melanoma antigen family A 1 (directs expression of antigen MZ2 E), Melanoma antigen MAGE 1, Melanoma associated antigen 1, Melanoma associated antigen MZ2 E, Melanoma-associated antigen 1, member 1, MGC9326
Reactivity:
Human
Immunogen:
Recombinant human MAGEA1 fragment
Applications:
WBIHCIF
Clonality:
Recombinant Monoclonal
Clone No:
C311217
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
MAGEA1
Conjugation:
Unconjugated
Observed MW:
46 kDa
Calculated MW:
34 kDa
Recommended Dilution:
WB 1:500-2000; IHC 1:50-200; IF 1:50
UniProt:
P43355
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Immunofluorescent analysis of (100% Ice-cold methanol) fixed HeLa cells using anti-MAGEA1 Monoclonal Antibody at dilution of 1: 50.
Immunohistochemistry of paraffin-embedded Human testis using MAGEA1 Monoclonal Antibody at dilution of 1: 100.
Western Blot with MAGEA1 Monoclonal Antibody at dilution of 1: 2000. Lane 1: A431 Observed-MW:46 kDa Calculated-MW:34 kDa