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Recombinant MDM2 Monoclonal Antibody (AGEL5650)

Datasheet MSDS
SKU AGEL5650
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110331
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant MDM2 Monoclonal Antibody

The Recombinant MDM2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110331) against MDM2. This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of A431. The target is localized to the cytoplasm, nucleus.

Product Name:Recombinant MDM2 Monoclonal Antibody
SKU:AGEL5650
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ACTFS, Double minute 2 protein, E3 ubiquitin-protein ligase Mdm2, hdm, Hdm 2, hdm2, HDMX, MDM, MDM 2, MDM2, MDM2 oncogene E3 ubiquitin protein ligase, Mdm2 p53 E3 ubiquitin protein ligase homolog, Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa, MDM2BP, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, Oncoprotein Mdm2, p53 Binding Protein Mdm2, p53-binding protein Mdm2, Ubiquitin protein ligase E3 Mdm2
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human MDM2 protein
Applications:WBIHCIFIPELISA
Clonality:Recombinant Monoclonal
Clone No:C110331
Host:Rabbit
Isotype:Rabbit IgG
Target:MDM2
Conjugation:Unconjugated
Observed MW:90 kDa
Calculated MW:55 kDa
Recommended Dilution:IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:Q00987
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Product ImageWestern Blot with Recombinant MDM2 Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: A431 whole cell lysate. Observed-MW:90 kDa Calculated-MW:55 kDa
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