Mouse Cathepsin D/CTSD Recombinant Protein (RPES0497)

SKU:
RPES0497
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Mouse
€196

Description

ELISA Kit Technical Manual

Recombinant Mouse Cathepsin D/CTSD Protein (His Tag)

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Background:CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.
Name:Recombinant Mouse Cathepsin D/CTSD Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES0497
Synonyms:Cathepsin D; CTSD;CPSD
Species:Mouse
Expression host:Human Cells
Sequence:Ile21-Leu410
Accession:NP_034113.1
Mol Mass:43.9 kDa
AP Mol Mass:56 kDa
Tag:C-6His
Purity:> 95 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 um filtered solution of 20mM MES,150mM NaCl,pH5.5.
Reconstitution:Please refer to it for detailed information.