The Recombinant Osteocalcin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111008) against Osteocalcin. This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HepG2. The target is localized to the secreted.
Product Name:
Recombinant Osteocalcin Monoclonal Antibody
SKU:
AGEL6314
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
BGLAP, BGP, Bone gamma carboxyglutamate (gla) protein, Bone gamma carboxyglutamate gla protein osteocalcin, Bone gamma carboxyglutamate protein, Bone Gamma-carboxyglutamate Protein, Bone Gla protein, Gamma carboxyglutamic acid containing protein, Gamma-carboxyglutamic acid-containing protein, OC, OCN, OSTCN, osteocalcin, OT, OTTHUMP00000016586, PMF, PMF1, ucOC
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Osteocalcin protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C111008
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Osteocalcin
Conjugation:
Unconjugated
Observed MW:
22 kDa
Calculated MW:
11 kDa
Recommended Dilution:
IHC 1:2000-10000; WB 1:100-500; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P02818
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.