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Recombinant p16 INK4A Monoclonal Antibody (AGEL5839)

Datasheet MSDS
SKU AGEL5839
Product Type Antibody
Reactivity Human, Mouse
Applications WB, IHC, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C220525
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant p16 INK4A Monoclonal Antibody

The Recombinant p16 INK4A Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C220525) against p16 INK4A. This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.

This antibody is suitable for WB, IHC, IP and ELISA applications. It has been validated by WB analysis of HEK293. The target is localized to the cytoplasm, nucleus.

Product Name:Recombinant p16 INK4A Monoclonal Antibody
SKU:AGEL5839
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ARF, CCM2, CDK4 inhibitor p16 INK4, CDK4I, CDKN, CDKN2, CDKN2A, Cell cycle negative regulator beta, CMM, CMM2, Cyclin dependent kinase 4 inhibitor A, Cyclin Dependent Kinase Inhibitor 2A, Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4), Cyclin dependent kinase inhibitor 2A isoform 4, Cyclin dependent kinase inhibitor 2A isoforms 1/2/3, Cyclin dependent kinase inhibitor p16, Cyclin-dependent kinase inhibitor 2A, INK, INK4, INK4A, MLM, MTS, MTS-1, MTS1, Multiple tumor suppressor 1, P14, P14ARF, P16, P16-INK4A, P16INK, P16INK4, P16INK4A, P19, P19ARF, TP16
Reactivity:Human, Mouse
Immunogen:Recombinant Human p16 INK4A protein
Applications:WBIHCIPELISA
Clonality:Recombinant Monoclonal
Clone No:C220525
Host:Rabbit
Isotype:Rabbit IgG
Target:p16 INK4A
Conjugation:Unconjugated
Observed MW:17 kDa
Calculated MW:17 kDa
Recommended Dilution:WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:P42771
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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