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Recombinant PDK2 Monoclonal Antibody (AGEL6652)

Datasheet MSDS
SKU AGEL6652
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C131347
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant PDK2 Monoclonal Antibody

The Recombinant PDK2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131347) against PDK2. [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of Mouse heart, Rat heart, A431, Neuro-2a, C6. The target is localized to the mitochondrion.

Product Name:Recombinant PDK2 Monoclonal Antibody
SKU:AGEL6652
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:[Pyruvate dehydrogenase [lipoamide]] kinase isozyme, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, isozyme, isozyme 2, mitochondrial, PDHK, PDHK2, PDK, PDK2, PDKII, Pyruvate dehydrogenase kinase, Pyruvate dehydrogenase kinase isoform, Pyruvate dehydrogenase kinase isoform 2, Pyruvate dehydrogenase lipoamide kinase isozyme, Pyruvate dehydrogenase lipoamide kinase isozyme 2
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human PDK2 fragment
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C131347
Host:Rabbit
Isotype:Rabbit IgG
Target:PDK2
Conjugation:Unconjugated
Observed MW:46 kDa
Calculated MW:46 kDa
Recommended Dilution:WB 1:1000-10000
UniProt:Q15119
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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