The Recombinant PEG10 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131580) against PEG10. Paternally expressed gene 10(PEG10) is an imprinted gene which is derived from a Ty3/Gypsy long terminal repeat (LTR) retrotransposon family encoding Gag- and Pol-like domains. Deletion of PEG10 in mice leads to embryonic lethality due to defects in placental formation. PEG10 is aberrantly expressed in several cancer types, including hepatocellular carcinoma, and contributes to tumorigenesis by affecting cell proliferation, apoptosis, and metastasis. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of HepG2, HeLa, Mouse placenta, Rat placenta. The target is localized to the cytoplasm, cell membrane, nucleus.
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with PEG10 Monoclonal Antibody at dilution of 1:1000. Lane 1: HepG2, Lane 2: HeLa, Lane 3: Mouse placenta, Lane 4: Rat placenta Observed-MW:55/100 kDa Calculated-MW:55/100 kDa