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Recombinant PERK Monoclonal Antibody (AGEL8573)

Datasheet MSDS
SKU AGEL8573
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C133268
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant PERK Monoclonal Antibody

The Recombinant PERK Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C133268) against PERK. The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis.It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of K562, C6, 3T3, Hela. The target is localized to the endoplasmic reticulum membrane.

Product Name:Recombinant PERK Monoclonal Antibody
SKU:AGEL8573
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:DKFZp781H1925, E2AK3, EC 2.7.11.1, Eif2ak3, Eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, Heme regulated EIF2 alpha kinase, HRI, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinas, Pancreatic eIF2-alpha kinase, PEK, PRKR like endoplasmic reticulum kinase, PRKR-like endoplasmic reticulum kinase, WRS
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein of human PERK
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C133268
Host:Rabbit
Isotype:Rabbit IgG
Target:PERK
Conjugation:Unconjugated
Observed MW:140 kDa
Calculated MW:125 kDa
Recommended Dilution:WB 1:500-1000
UniProt:Q9NZJ5
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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