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Key Features

Recombinant PERK Monoclonal Antibody (AGEL5941)

Datasheet MSDS
SKU AGEL5941
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C170629
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant PERK Monoclonal Antibody

The Recombinant PERK Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170629) against PERK. The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IF and ELISA applications. It has been validated by WB analysis of HeLa, MCF7, Mouse brain, Rat brain. The target is localized to the endoplasmic reticulum membrane.

Product Name:Recombinant PERK Monoclonal Antibody
SKU:AGEL5941
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:DKFZp781H1925, E2AK3, EC 2.7.11.1, EIF2AK, EIF2AK3, eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, Heme regulated EIF2 alpha kinase, HRI, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinase, PEK, PERK, PRKR like endoplasmic reticulum kinase, PRKR-like endoplasmic reticulum kinase, WRS
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human PERK protein
Applications:WBIFELISA
Clonality:Recombinant Monoclonal
Clone No:C170629
Host:Rabbit
Isotype:Rabbit IgG
Target:PERK
Conjugation:Unconjugated
Observed MW:140 kDa
Calculated MW:125 kDa
Recommended Dilution:WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:Q9NZJ5
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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