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Key Features

Recombinant PRAS40 Monoclonal Antibody (AGEL6804)

Datasheet MSDS
SKU AGEL6804
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC
Host Species Rabbit
Clonality Monoclonal
Clone C121499
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant PRAS40 Monoclonal Antibody

The Recombinant PRAS40 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121499) against PRAS40. PRAS40 is a proline-rich protein with a molecular weight of 40 kDa that acts as a substrate for the serine / threonine kinase Akt. PRAS40 also binds mTOR to transduce Akt signals to the mTOR complex. Inhibition of mTOR signaling stimulates PRAS40 binding to mTOR, which in turn inhibits mTOR activity. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of MCF-7, HeLa, PC-12 and IHC analysis of Human breast cancer, Mouse liver, Rat cardiac muscle. The target is localized to the cytoplasm.

Product Name:Recombinant PRAS40 Monoclonal Antibody
SKU:AGEL6804
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:AKT1 substrate, AKT1 substrate 1, AKT1S, AKT1S1, Lobe, PRAS, PRAS40
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human PRAS40 fragment
Applications:WBIHC
Clonality:Recombinant Monoclonal
Clone No:C121499
Host:Rabbit
Isotype:Rabbit IgG
Target:PRAS40
Conjugation:Unconjugated
Observed MW:40 kDa
Calculated MW:27 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50-200
UniProt:Q96B36
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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