The Recombinant PUMA Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110439) against PUMA. This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the mitochondrion.
Product Name:
Recombinant PUMA Monoclonal Antibody
SKU:
AGEL5756
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
BBC, BBC 3, BBC3, BBC3_HUMAN, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA, PUMA alpha, PUMA/JFY1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human PUMA protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110439
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
PUMA
Conjugation:
Unconjugated
Observed MW:
21 kDa
Calculated MW:
21 kDa
Recommended Dilution:
IHC 1:500-2000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
Q9BXH1
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.