The Recombinant Rab11 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110935) against Rab11. The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of A549. The target is localized to the cell membrane, lipid-anchor, recycling endosome membrane, lipid-anchor, cleavage furrow, cytoplasmic vesicle, phagosome, cytoplasmic vesicle membrane, Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (PubMed:11994279). Localizes to the cleavage furrow (PubMed:15601896). Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis (PubMed:20890297). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). Recycling endosome membrane, lipid-anchor, cytoplasmic side, cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, lipid-anchor, cytoplasmic side, cytoplasmic vesicle, phagosome membrane, lipid-anchor, cytoplasmic side, Recruited to phagosomes containing S.aureus.
Product Name:
Recombinant Rab11 Monoclonal Antibody
SKU:
AGEL6241
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
member oncogene family, MGC, MGC1490, Rab 11, Rab 11A, Rab-11, RAB11, RAB11 A, RAB11A, RAB11A member RAS oncogene family, Ras related protein Rab 11A, Ras related protein Rab11A, Ras-related protein Rab-11A, RB11A, YL 8, YL8
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Rab11 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110935
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Rab11
Conjugation:
Unconjugated
Observed MW:
24 kDa
Calculated MW:
24 kDa
Recommended Dilution:
IHC 1:1000-5000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P62491, Q15907
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
