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Recombinant RGS6 Monoclonal Antibody (AGEL6163)

Datasheet MSDS
SKU AGEL6163
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C130857
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant RGS6 Monoclonal Antibody

The Recombinant RGS6 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C130857) against RGS6. This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of HeLa. The target is localized to the Cytoplasm {ECO:0000269|PubMed:12761221}. Cytoplasm, cytosol {ECO:0000269|PubMed:10521509}. Membrane {ECO:0000269|PubMed:10521509}; Peripheral membrane protein {ECO:0000269|PubMed:10521509}. Nucleus {ECO:0000269|PubMed:12761221}. Cell membrane {ECO:0000250|UniProtKB:Q9Z2H2}. Note: Interaction with GNB5 mediates translocation to the nucleus. {ECO:0000269|PubMed:12761221}.

Product Name:Recombinant RGS6 Monoclonal Antibody
SKU:AGEL6163
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:RGS, RGS6
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human RGS6 protein
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C130857
Host:Rabbit
Isotype:Rabbit IgG
Target:RGS6
Conjugation:Unconjugated
Observed MW:52 kDa
Calculated MW:52 kDa
Recommended Dilution:WB 1:1000-5000
UniProt:P49758
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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