The Recombinant SIRT1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C710725) against SIRT1. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the nuclear.
Product Name:
Recombinant SIRT1 Monoclonal Antibody
SKU:
AGEL6033
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
75SirT, 75SirT1, homolog of, homolog-like, homolog-like 1, Hsir, Hsir2, Hsirt, Hsirt1, HST, HST2, NAD dependent deacetylase sirtuin 1, NAD dependent protein deacetylase sirtuin 1, NAD-dependent deacetylase sirtuin, NAD-dependent deacetylase sirtuin-1, OTTHUMP00000198111, OTTHUMP00000198112, Regulatory protein SIR2 homolog, Regulatory protein SIR2 homolog 1, S. cerevisiae, S.cerevisiae, SIR, SIR1, SIR2, SIR2 like 1, SIR2 like protein, SIR2 like protein 1, SIR2-like protein 1, SIR2alpha, SIR2L, SIR2L1, SIRT, SIRT1, SirtT1 75 kDa fragment, sirtuin, Sirtuin (silent mating type information regulation 2 homolog), Sirtuin (silent mating type information regulation 2 homolog) 1, Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), sirtuin 1, Sirtuin type 1
Reactivity:
Human, Rat
Immunogen:
Recombinant Human SIRT1 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C710725
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SIRT1
Conjugation:
Unconjugated
Observed MW:
130 kDa
Calculated MW:
81 kDa
Recommended Dilution:
IHC 1:100-200; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q96EB6
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.