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Recombinant Smac/Diablo Monoclonal Antibody (AGEL6586)

Datasheet MSDS
SKU AGEL6586
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC, IF, FCM, IP
Host Species Rabbit
Clonality Monoclonal
Clone C111281
Conjugate Unconjugated
€459 - €639

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Description

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Recombinant Smac/Diablo Monoclonal Antibody

The Recombinant Smac/Diablo Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111281) against Smac/Diablo. Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, FCM and IP applications. It has been validated by WB analysis of Jurkat, MCF-7, HepG2, C2C12, C6, IHC analysis of Human lung squamous carcinoma, IF analysis of HeLa, FCM analysis of Jurkat and IP analysis of Jurkat cells extracts. The target is localized to the mitochondrion.

Product Name:Recombinant Smac/Diablo Monoclonal Antibody
SKU:AGEL6586
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:0610041G12Rik, DBLOH, DBOH, DFNA, DFNA64, DIABLO, Diablo homolog, Diablo homolog (Drosophila), Diablo homolog mitochondrial, Diablo IAP binding mitochondrial protein, Diablo like protein, DIABLO S, Direct IAP binding protein with low pI, Direct IAP-binding protein with low pI, FLJ10537, FLJ25049, mitochondrial, Mitochondrial Smac protein, Second mitochondria derived activator of caspase, Second mitochondria-derived activator of caspase, SMAC, SMAC 3, Smac protein, SMAC3
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human Smac/Diablo fragment
Applications:WBIHCIFFCMIP
Clonality:Recombinant Monoclonal
Clone No:C111281
Host:Rabbit
Isotype:Rabbit IgG
Target:Smac/Diablo
Conjugation:Unconjugated
Observed MW:21 kDa
Calculated MW:27 kDa
Recommended Dilution:WB 1:500-2000; IHC 1:50-100; IF 1:500-1000; FCM 1:50-100; IP 1:25-100
UniProt:Q9NR28
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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