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Key Features

Recombinant SMARCA2 Monoclonal Antibody (AGEL8602)

Datasheet MSDS
SKU AGEL8602
Product Type Antibody
Reactivity Human
Applications WB, IHC-P
Host Species Rabbit
Clonality Monoclonal
Clone C323297
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant SMARCA2 Monoclonal Antibody

The Recombinant SMARCA2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C323297) against SMARCA2. The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of A549, HL-60, U2OS and IHC analysis of Human lung cancer. The target is localized to the nucleus.

Product Name:Recombinant SMARCA2 Monoclonal Antibody
SKU:AGEL8602
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ATP dependent helicase SMARCA2, ATP-dependent helicase SMARCA2, BAF190, BAF190B, BRG1-associated factor 190B, BRM, FLJ36757, Global transcription activator homologous sequence, hBRM, hSNF2a, MGC74511, Possible global transcription activator SNF2L2, Probable global tr, Probable global transcription activator SNF2L2, Protein brahma homolog, SMARCA2, SMCA2, SNF2 alpha, SNF2 like 2, SNF2-alpha, SNF2/SWI2 like protein 2, SNF2L2, SNF2LA, Sth1p, Sucrose nonfermenting 2 like protein 2, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Reactivity:Human
Immunogen:A synthetic peptide of human SMARCA2/BRM
Applications:WBIHC-P
Clonality:Recombinant Monoclonal
Clone No:C323297
Host:Rabbit
Isotype:Rabbit IgG
Target:SMARCA2
Conjugation:Unconjugated
Observed MW:190 kDa
Calculated MW:181 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50-100
UniProt:P51531
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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