The Recombinant Sox2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110094) against Sox2. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF and FC applications. It has been validated by WB analysis of MCF-7, Mouse brain, Mouse embryo, Mouse fetal brain, C6, Rat brain, Rat embryo, Rat fetal brain and IHC analysis of Human glioma, Mouse brain, Rat brain. The target is localized to the nuclear.
Product Name:
Recombinant Sox2 Monoclonal Antibody
SKU:
AGEL5413
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ANOP, ANOP3, cb236, Delta EF2a, lcc, MCOPS, MCOPS3, MGC148683, MGC2413, RGD1565646, Sex determining region Y box 2, SOX, SOX 2, SOX2, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box, SRY-box 2, Transcription factor SOX 2, Transcription factor SOX-2, ysb
Reactivity:
Human, Mouse, Rat
Immunogen:
A synthetic peptide corresponding to the N-terminus of the human Sox2.