The Recombinant SOX2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111285) against SOX2. Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell pluripotency. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC and IF applications. It has been validated by WB analysis of MCF-7, Mouse brain, IHC analysis of Human lung adenocarcinoma, Human prostate hyperplasia, Mouse stomach, Rat stomach and IF analysis of F9. The target is localized to the nucleus.
Product Name:
Recombinant SOX2 Monoclonal Antibody
SKU:
AGEL6590
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ANOP, ANOP3, cb236, Delta EF2a, lcc, MCOPS, MCOPS3, MGC148683, MGC2413, RGD1565646, Sex determining region Y box 2, SOX, SOX 2, SOX2, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box, SRY-box 2, Transcription factor SOX 2, Transcription factor SOX-2, ysb
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human SOX2 fragment
Applications:
WBIHCIF
Clonality:
Recombinant Monoclonal
Clone No:
C111285
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SOX2
Conjugation:
Unconjugated
Observed MW:
34 kDa
Calculated MW:
34 kDa
Recommended Dilution:
WB 1:500-1000; IHC 1:200-1000; IF 1:50
UniProt:
P48431
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.