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Recombinant Survivin Monoclonal Antibody (AGEL8700)

Datasheet MSDS
SKU AGEL8700
Product Type Antibody
Reactivity Human
Applications WB, IF
Host Species Rabbit
Clonality Monoclonal
Clone C373395
Conjugate Unconjugated
$461 - $632

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Description

system_update_altDatasheetsystem_update_altMSDS

Recombinant Survivin Monoclonal Antibody

The Recombinant Survivin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C373395) against Survivin. This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB and IF applications. It has been validated by WB analysis of Jurkat and IF analysis of MCF-7. The target is localized to the Cytoplasm. Nucleus. Chromosome. Chromosome>centromere. Cytoplasm>cytoskeleton>spindle. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes.

Product Name:Recombinant Survivin Monoclonal Antibody
SKU:AGEL8700
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Apoptosis inhibitor4, Baculoviral IAP repeat containing 5, Baculoviral IAP repeat containing protein 5, Baculoviral IAP repeat-containing protein 5, BIRC 5, BIRC5, EPR 1, IAP4, Survivin variant 3 alpha, SVV, TIAP
Reactivity:Human
Immunogen:Recombinant protein of human Survivin
Applications:WBIF
Clonality:Recombinant Monoclonal
Clone No:C373395
Host:Rabbit
Isotype:Rabbit IgG
Target:Survivin
Conjugation:Unconjugated
Observed MW:16 kDa
Calculated MW:16 kDa
Recommended Dilution:WB 1:500-1000; IF 1:20-100
UniProt:O15392
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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