The Recombinant SUV39H2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121439) against SUV39H2. SUV39H2, also known as KMT1B, is a member of the SUV39 subfamily of lysine methyltransferases (KMTs) that plays a significant role in histone H3-K9 di-/Trimethylation, transcriptional regulation and cell cycle. Overexpressions of SUV39H2 at gene, mRNA and protein levels are known to be associated with a range of cancers: leukemia, lymphomas, lung cancer, breast cancer, colorectal cancer, gastric cancer, hepatocellular cancer and so on. Accumulating evidence indicates that SUV39H2 acts as an oncogene and contributes to the initiation and progression of cancers. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa, HEK-293T, MOLT-4, NIH/3T3 and IHC analysis of Mouse testis, Rat testis. The target is localized to the nucleus.
Product Name:
Recombinant SUV39H2 Monoclonal Antibody
SKU:
AGEL6744
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
FLJ23414, H3 K9 HMTase 2, H3-K9-HMTase 2, Histone H3 K9 methyltransferase 2, Histone H3-K9 methyltransferase 2, Histone lysine N methyltransferase H3 lysine 9 specific 2, Histone lysine N methyltransferase SUV39H2, Histone-lysine N-methyltransferase SUV39H2, KMT1B, Lysine N methyltransferase 1B, Lysine N-methyltransferase 1B, sSuppressor of variegation 3 9 homolog 2 (Drosophila), Su(var)3 9 Drosophila homolog of 2, Su(var)3 9 homolog 2, Su(var)3-9 homolog 2, Suppressor of variegation 3 9 homolog 2, Suppressor of variegation 3-9 homolog 2, SUV39H, SUV39H2, SUV92
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human SUV39H2 fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C121439
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SUV39H2
Conjugation:
Unconjugated
Observed MW:
47, 50 kDa
Calculated MW:
47 kDa
Recommended Dilution:
WB 1:500-1000; IHC 1:50-100
UniProt:
Q9H5I1
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
