The Recombinant Thioredoxin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110877) against Thioredoxin. The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by IHC analysis of thyroid carcinoma. The target is localized to the nucleus, cytoplasm, secreted, Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947).
![Anti-Thioredoxin 2 [R01-7C7] Monoclonal Antibody (AGMB00332)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/271621/692069/anti-thioredoxin-2-r01-7c7-monoclonal-antibody-agmb00332__32014.1774505004.jpg?c=2 "Anti-Thioredoxin 2 [R01-7C7] Monoclonal Antibody (AGMB00332)")