The Recombinant TTF1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110271) against TTF1. This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of A549, HepG2, HeLa, U-251, HT-1080. The target is localized to the nuclear.
Product Name:
Recombinant TTF1 Monoclonal Antibody
SKU:
AGEL5590
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
AV026640, BCH, Benign chorea, BHC, drosophila, Homeobox protein NK 2 homolog A, Homeobox protein NK-2 homolog A, Homeobox protein Nkx 2.1, Homeobox protein Nkx-2.1, Homeobox protein Nkx2.1, homolog of, mouse, NK 2, NK 2 homolog A, NK-2, NK2, NK2 homeobox 1, NK2.1, NKX, Nkx 2 1, NKX 2.1, NKX 2A, NKX2 1, NKX2-, NKX2-1, NKX2.1, NKX21, NKX2A, NMTC, NMTC1, T EBP, T/EBP, TEBP, Thyroid nuclear factor, Thyroid nuclear factor 1, Thyroid specific enhancer binding protein, Thyroid transcription factor 1, Tin man, Tinman, TITF, TITF 1, TITF1, TTF, TTF 1, TTF-1, TTF1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human TTF1 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110271
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
TTF1
Conjugation:
Unconjugated
Observed MW:
40 kDa
Calculated MW:
40 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P43699
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.