The Recombinant ZWINT Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C320859) against ZWINT. This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC and FC applications. It has been validated by WB analysis of HeLa. The target is localized to the Nucleus. Chromosome, centromere, kinetochore. localizes to kinetochores from late prophase to anaphase.
