Description
RFX2 Transcription Factor Activity Assay
The RFX2 Transcription Factor Activity Assay is a cutting-edge research tool designed to measure the activity of RFX2, a key transcription factor involved in the regulation of gene expression. This assay provides researchers with a reliable and accurate method for studying the role of RFX2 in various biological processes, including immune response, development, and disease progression.With its high sensitivity and specificity, the RFX2 Transcription Factor Activity Assay ensures precise measurement of RFX2 activity in a variety of samples, including cell lysates and tissue homogenates.
This kit offers reproducible results, allowing researchers to confidently analyze the impact of RFX2 dysregulation on gene expression and cellular function.Whether investigating the molecular mechanisms underlying immune disorders, developmental abnormalities, or cancer progression, the RFX2 Transcription Factor Activity Assay is an invaluable tool for researchers seeking to unravel the intricate networks of gene regulation. Stay ahead of the curve and advance your research with this innovative assay from AssayGenie.
| Product Name: | RFX2 Transcription Factor Activity Assay |
| Product Code: | TFAB00156 |
| Target: | RFX2 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie RFX2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | RFX2: a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; nucleus Molecular Function:DNA binding; transcription factor activity Biological Process: acrosome formation; cilium biogenesis; regulation of transcription from RNA polymerase II promoter; spermatid development |
| NCBI Summary: | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P48378 |
| NCBI GenInfo Identifier: | 254763325 |
| NCBI Gene ID: | 5990 |
| NCBI Accession: | P48378.2 |
| UniProt Secondary Accession: | P48378,Q6IQ44, Q8SNA2, A8K581, B3KNC4, |
| UniProt Related Accession: | P48378 |
| Molecular Weight: | 77,268 Da |
| NCBI Full Name: | DNA-binding protein RFX2 |
| NCBI Synonym Full Names: | regulatory factor X2 |
| NCBI Official Symbol: | RFX2 |
| NCBI Protein Information: | DNA-binding protein RFX2 |
| UniProt Protein Name: | DNA-binding protein RFX2 |
| UniProt Synonym Protein Names: | Regulatory factor X 2 |
| Protein Family: | RFX-like DNA-binding protein |
| UniProt Gene Name: | RFX2 |
| UniProt Entry Name: | RFX2_HUMAN |
