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Anti-SFRP1 Antibody (CAB2911)

SKU:
CAB2911
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Developmental Biology
  • Developmental Biology Anti-SFRP1 Antibody CAB2911
  • Developmental Biology Anti-SFRP1 Antibody CAB2911
€139 - €419
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Description

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Antibody Name:Anti-SFRP1 Antibody
Antibody SKU:CAB2911
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3).
Application:WB IHC
Recommended Dilution:WB 1:100 - 1:500 IHC 1:50 - 1:100
Reactivity:Human, Mouse
Positive Samples:NCI-H460, 293T, SKOV3, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SASE YDYV SFQS DIGP YQSG RFYT KPPQ CVDI PADL RLCH NVGY KKMV LPNL LEHE TMAE VKQQ ASSW VPLL NKNC HAGT QVFL CSLF APVC LDRP IYPC RWLC EAVR DSCE PVMQ FFGF YWPE MLKC DKFP EGDV CIAM TPPN ATEA SKPQ GTTV CPPC DNEL KSEA IIEH LCAS EFAL RMKI KEVK KENG DKKI VPKK KKPL KLGP IKKK DLKK LVLY LKNG ADCP CHQL DNLS HHFL IMGR KVKS QYLL TAIH KWDK KNKE FKNF MKKM KNHE CPTF QSVF K
Gene ID:6422
Uniprot:Q8N474
Cellular Location:Secreted
Calculated MW:35kDa
Observed MW:35kDa
Synonyms:SFRP1, FRP, FRP-1, FRP1, FrzA, SARP2
Background:This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
UniProt Code:Q8N474
NCBI GenInfo Identifier:61216811
NCBI Gene ID:6422
NCBI Accession:Q8N474.1
UniProt Secondary Accession:Q8N474,O00546, O14779,
UniProt Related Accession:Q8N474
Molecular Weight:314
NCBI Full Name:Secreted frizzled-related protein 1
NCBI Synonym Full Names:secreted frizzled-related protein 1
NCBI Official Symbol:SFRP1  
NCBI Official Synonym Symbols:FRP; FRP1; FrzA; FRP-1; SARP2  
NCBI Protein Information:secreted frizzled-related protein 1; SARP-2; sFRP-1; secreted apoptosis-related protein 2
UniProt Protein Name:Secreted frizzled-related protein 1
UniProt Synonym Protein Names:Secreted apoptosis-related protein 2; SARP-2
Protein Family:Secreted frizzled-related protein
UniProt Gene Name:SFRP1  
UniProt Entry Name:SFRP1_HUMAN
Anti-SFRP1 Antibody (CAB2911)Western blot analysis of extracts of various cell lines, using SFRP1 antibody (CAB2911) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-SFRP1 Antibody (CAB2911)Immunohistochemistry of paraffin-embedded human stomach using SFRP1 antibody (CAB2911) at dilution of 1:50 (20x lens).

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