Anti-SLC27A1 Antibody (CAB12847)

Antibody Name:	Anti-SLC27A1 Antibody
Antibody SKU:	CAB12847
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 347-646 of human SLC27A1 (NP_940982.1).

Application:	WB
Recommended Dilution:	WB 1:1000 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	U2OS, MCF-7, Mouse skeletal muscle, Mouse heart, Rat heart

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 347-646 of human SLC27A1 (NP_940982.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	QPVR EAER RHRV RLAV GNGL RPAI WEEF TERF GVRQ IGEF YGAT ECNC SIAN MDGK VGSC GFNS RILP HVYP IRLV KVNE DTME LLRD AQGL CIPC QAGE PGLL VGQI NQQD PLRR FDGY VSES ATSK KIAH SVFS KGDS AYLS GDVL VMDE LGYM YFRD RSGD TFRW RGEN VSTT EVEG VLSR LLGQ TDVA VYGV AVPG VEGK AGMA AVAD PHSL LDPN AIYQ ELQK VLAP YARP IFLR LLPQ VDTT GTFK IQKT RLQR EGFD PRQT SDRL FFLD LKQG HYLP LNEA VYTR ICSG AFAL
Gene ID:	376497
Uniprot:	Q6PCB7
Cellular Location:	Cell membrane, Cytoplasm, Endomembrane system, Single-pass membrane protein
Calculated MW:	51kDa/71kDa
Observed MW:	71kDa

Synonyms:	SLC27A1, ACSVL5, FATP, FATP-1, FATP1
Background:

UniProt Protein Function:	SLC27A1: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane- associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family.
UniProt Protein Details:	Protein type:EC 6.2.1.-; Ligase; Lipid-binding; Membrane protein, integral; Mitochondrial; Vesicle Chromosomal Location of Human Ortholog: 19p13.11 Cellular Component: membrane; plasma membrane Molecular Function:fatty acid transporter activity Biological Process: cardiolipin biosynthetic process; long-chain fatty acid transport; phosphatidic acid biosynthetic process; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylglycerol biosynthetic process; phosphatidylinositol biosynthetic process; phosphatidylserine biosynthetic process
UniProt Code:	Q6PCB7
NCBI GenInfo Identifier:	38524616
NCBI Gene ID:	376497
NCBI Accession:	NP_940982.1
UniProt Secondary Accession:	Q6PCB7,A6NIH2, B7Z662,
UniProt Related Accession:	Q6PCB7
Molecular Weight:
NCBI Full Name:	long-chain fatty acid transport protein 1
NCBI Synonym Full Names:	solute carrier family 27 member 1
NCBI Official Symbol:	SLC27A1
NCBI Official Synonym Symbols:	FATP; FATP1; ACSVL5; FATP-1
NCBI Protein Information:	long-chain fatty acid transport protein 1
UniProt Protein Name:	Long-chain fatty acid transport protein 1
UniProt Synonym Protein Names:	Solute carrier family 27 member 1
UniProt Gene Name:	SLC27A1
UniProt Entry Name:	S27A1_HUMAN

Western blot analysis of extracts of various cell lines, using SLC27A1 antibody (CAB12847) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.

ELISA Kits

Human Long-chain fatty acid transport protein 1 (SLC27A1) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)