The SLCO1A2 Antibody (CAB8452) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, reacts specifically with human samples and is validated for use in Western blot applications.SLCO1A2 plays a crucial role in drug absorption, distribution, and elimination, making it a target of interest in pharmacology and drug metabolism studies. By detecting and analyzing the SLCO1A2 protein in different cell types, researchers can gain insight into its function and potential implications for drug transport and metabolism.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.
Product Name:
SLCO1A2 Antibody
SKU:
CAB8452
Size:
20μL, 100μL
Reactivity:
Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:
SYEG IPQD LYVE NDIF ADC
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:5000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
OATP, OATP-A, OATP1A2, SLC21A3, SLCO1A2
Positive Sample:
Rat liver
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
74kDa
Observed MW:
74kDa
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
6579
RRID
AB_2772293
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Rat liver, using SLCO1A2 Rabbit pAb (CAB8452) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
