The STX6 Antibody (CAB16283) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly reactive with human and other mammalian samples and is validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.STX6 is a critical regulator of vesicle trafficking and membrane fusion events within the cell. It plays a key role in the transport of cargo between the trans-Golgi network and endosomes, as well as in the recycling of endocytic vesicles. Dysregulation of STX6 has been implicated in various diseases, including neurodegenerative disorders, infectious diseases, and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
STX6 Antibody
SKU:
CAB16283
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
STX6
Positive Sample:
bewo, SK-BR-3, Mouse brain, Mouse thymus
Cellular Localization:
Golgi Apparatus Membrane, Single-Pass Type Iv Membrane Protein.
Calculated MW:
29kDa
Observed MW:
35kDa
Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex.
Purification Method
Affinity purification
Gene ID
10228
RRID
AB_2772454
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using STX6 Rabbit pAb (CAB16283) at 1:800 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
