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TNFRSF10A Rabbit Polyclonal Antibody (CAB12540)

SKU:
CAB12540
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-TNFRSF10A Antibody CAB12540
  • Cell Death Antibodies 1 Anti-TNFRSF10A Antibody CAB12540
  • Cell Death Antibodies 1 Anti-TNFRSF10A Antibody CAB12540
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TNFRSF10A Rabbit Polyclonal Antibody
SKU:CAB12540
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 269-468 of human TNFRSF10A (NP_003835.3).
Sequence:GGDP KCMD RVCF WRLG LLRG PGAE DNAH NEIL SNAD SLST FVSE QQME SQEP ADLT GVTV QSPG EAQC LLGP AEAE GSQR RRLL VPAN GADP TETL MLFF DKFA NIVP FDSW DQLM RQLD LTKN EIDV VRAG TAGP GDAL YAML MKWV NKTG RNAS IHTL LDAL ERME ERHA REKI QDLL VDSG KFIY LEDG TGSA VSLE
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100
Synonyms:DR4; APO2; CD261; TRAILR1; TRAILR-1; TNFRSF10A
Positive Sample:K-562,SW480,MCF7,HeLa,DU145,Mouse lung,Rat lung
Conjugate:Unconjugated
Cellular Localization:Membrane, Single-pass type I membrane protein.
Calculated MW:50kDa
Observed MW:40-55kDa

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

Purification Method:Affinity purification
Gene ID:8797
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using TNFRSF10A antibody (CAB12540) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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