The TRPC1 Monoclonal Antibody (CAB4016) is a high-quality antibody developed for reliable detection and analysis of target proteins. The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. RRID AB_2863173 Gene ID 7220 Swiss Prot Synonym TRP1; HTRP-1; TRPC1
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
TRPC1 Monoclonal Antibody
SKU:
CAB4016
Size:
100μL, 20μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0884
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TRP1, HTRP-1, TRPC1
Positive Sample:
A549, PC-3, U-251MG, Mouse brain, Rat brain
Cellular Localization:
Membrane.
Calculated MW:
88kDa/91kDa
Observed MW:
130kDa
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. RRID AB_2863173 Gene ID 7220 Swiss Prot Synonym TRP1; HTRP-1; TRPC1
Purification Method:
Affinity purification
Gene ID:
7220
RRID:
AB_2863173
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using TRPC1 Rabbit mAb (CAB4016) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
