UniProt Protein Function: | UPRT: an enzyme which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]Protein type: EC 2.4.2.9; Transferase; Nucleotide Metabolism - pyrimidineChromosomal Location of Human Ortholog: Xq13.3Cellular Component: cytosolMolecular Function: protein binding; uridine kinase activityBiological Process: pyrimidine base metabolic process; pyrimidine nucleoside salvage |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009] |
UniProt Code: | Q96BW1 |
NCBI GenInfo Identifier: | 74751783 |
NCBI Gene ID: | 139596 |
NCBI Accession: | Q96BW1.1 |
UniProt Secondary Accession: | Q96BW1,Q5JRL1, Q5JRL3, Q68DN0, Q96MW2 |
UniProt Related Accession: | Q96BW1 |
Molecular Weight: | 19,056 Da |
NCBI Full Name: | Uracil phosphoribosyltransferase homolog |
NCBI Synonym Full Names: | uracil phosphoribosyltransferase homolog |
NCBI Official Symbol: | UPRTÂ Â |
NCBI Official Synonym Symbols: | UPP; FUR1Â Â |
NCBI Protein Information: | uracil phosphoribosyltransferase homolog |
UniProt Protein Name: | Uracil phosphoribosyltransferase homolog |
UniProt Synonym Protein Names: | |
Protein Family: | Uracil phosphoribosyltransferase |
UniProt Gene Name: | UPRTÂ Â |
UniProt Entry Name: | UPP_HUMAN |