Anti-UQCRC2 Antibody (CAB4366)

Product Name:	UQCRC2 Rabbit mAb
Product Code:	CAB4366
Size:	20uL, 50uL, 100uL
Synonyms:	MC3DN5, QCR2, UQCR2
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthesized peptide derived from human UQCRC2

Applications:	WB, IHC
Recommended Dilutions:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	293T, HepG2, A-549, Mouse heart, Rat brain, Rat heart

Immunogen:	A synthesized peptide derived from human UQCRC2
Purification Method:	Affinity purification
Storage:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	7385
Uniprot:	P22695
Cellular Location:	Matrix side, Mitochondrion inner membrane, Peripheral membrane protein
Calculated MW:	48kDa
Observed MW:	48KDa

UniProt Protein Function:	UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
UniProt Protein Details:	Protein type:EC 1.10.2.2; Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 16p12 Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III Molecular Function:protein binding; metal ion binding; metalloendopeptidase activity; protein complex binding Biological Process: cellular metabolic process; aerobic respiration; proteolysis; oxidative phosphorylation Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5
NCBI Summary:	The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]
UniProt Code:	P22695
NCBI GenInfo Identifier:	21903482
NCBI Gene ID:	7385
NCBI Accession:	P22695.3
UniProt Secondary Accession:	P22695,Q9DB77, P32551,
UniProt Related Accession:	P22695
Molecular Weight:	48kDa
NCBI Full Name:	Cytochrome b-c1 complex subunit 2, mitochondrial
NCBI Synonym Full Names:	ubiquinol-cytochrome c reductase core protein 2
NCBI Official Symbol:	UQCRC2
NCBI Official Synonym Symbols:	QCR2; UQCR2; MC3DN5
NCBI Protein Information:	cytochrome b-c1 complex subunit 2, mitochondrial
UniProt Protein Name:	Cytochrome b-c1 complex subunit 2, mitochondrial
UniProt Synonym Protein Names:	Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2
UniProt Gene Name:	UQCRC2
UniProt Entry Name:	QCR2_HUMAN