ADA2L Transcription Factor Activity Assay

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ELISA Kit Technical ManualMSDS

ADA2L Transcription Factor activity assay

Product Description:The ELISA Genie ADA2L transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates ELISA Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:Transcriptional adapter 2-like Short name: ADA2-like protein
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse, Rat
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4°C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

ADA2L Transcription Factor activity assay Protein Information

UniProt Protein Function:Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.
NCBI Summary:Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]
UniProt Code:O75478
NCBI GenInfo Identifier:317373498
NCBI Gene ID:6871
NCBI Accession:O75478.3
UniProt Secondary Accession:O75478,Q9BVJ0, Q9UCW2, Q9UP49, A8MVD0, B3KMU9,
UniProt Related Accession:O75478,AAB50689
Molecular Weight:36,054 Da
NCBI Full Name:Transcriptional adapter 2-alpha
NCBI Synonym Full Names:transcriptional adaptor 2A
NCBI Official Symbol:TADA2A
NCBI Official Synonym Symbols:ADA2; ADA2A; KL04P; hADA2; TADA2L
NCBI Protein Information:transcriptional adapter 2-alpha
UniProt Protein Name:Transcriptional adapter 2-alpha
UniProt Synonym Protein Names:Transcriptional adapter 2-like; ADA2-like protein
Protein Family:Transcriptional adapter
UniProt Gene Name:TADA2A
UniProt Entry Name:TAD2A_HUMAN
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