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ADORA1 Rabbit Polyclonal Antibody (CAB18525)

SKU:
CAB18525
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ADORA1 Rabbit Polyclonal Antibody
SKU:CAB18525
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-326 of human ADORA1 (NP_000665.1).
Sequence:LHIL NCIT LFCP SCHK PSIL TYIA IFLT HGNS AMNP IVYA FRIQ KFRV TFLK IWND HFRC QPAP PIDE DLPE ERPD D
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:RDC7; ADORA1
Positive Sample:Mouse heart
Cellular Localization:basolateral plasma membrane, calyx of Held, dendrite, dendritic spine, endoplasmic reticulum, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic active zone, presynaptic membrane, synapse, terminal bouton
Calculated MW:37kDa
Observed MW:37kDa

The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.

Purification Method:Affinity purification
Gene ID:134
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse heart, using ADORA1 Rabbit pAb (CAB18525) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.

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