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APC Anti-Mouse CD4 Antibody [RM4-5] (AGEL3495)

Datasheet MSDS
SKU AGEL3495
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, k
Clone RM4-5
Conjugation APC
$55 - $164

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Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Mouse CD4 Antibody [RM4-5]

The Anti-Mouse CD4 Antibody (RM4-5) is a highly specific and reliable tool designed for researchers studying CD4, a critical cell surface marker involved in immune responses. This monoclonal antibody is sourced from hybridoma cells and has been extensively validated for use in various experimental applications, including flow cytometry and immunohistochemistry.CD4, a glycoprotein found on the surface of T helper cells, plays a crucial role in immune system function by interacting with major histocompatibility complex (MHC) class II molecules on antigen-presenting cells. The RM4-5 Antibody recognizes and binds specifically to CD4, enabling researchers to accurately identify and study CD4-positive cells in complex biological samples.

Studies involving CD4 are instrumental in understanding immune system dynamics, including T cell activation, differentiation, and regulatory processes. This antibody is a valuable tool for investigations into various immune-related disorders, infectious diseases, and the development of immunotherapies. Its high specificity, sensitivity, and consistency make it a reliable choice for researchers in immunology, oncology, and related fields aiming to unravel the complexities of immune responses.

Product Title:APC Anti-Mouse CD4 Antibody [RM4-5]
SKU:AGEL3495
Size:25µg, 100µg
Clone No:RM4-5
Synonyms:T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;L3T4;T4;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P06332
Gene ID:12504
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes and a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a co-receptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase lck.
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