ApoM Rabbit Monoclonal Antibody (CAB5144)

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CAB5144
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Description

Technical Manual

ApoM Rabbit Monoclonal Antibody

Product Name:ApoM Rabbit Monoclonal Antibody
Product SKU:CAB5144
Size:20uL, 50 uL
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Background:

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]

Immunogen:A synthesized peptide derived from human ApoM
Sequence:

Email for sequence

Gene ID:55937
Swiss Prot:O95445
Synonyms:G3a; HSPC336; NG20; apo-M
Calculated MW:25kDa
Observed MW:21KDa
Reactivity:Human, Mouse
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Application Key:Western blotting Immunofluorescence 
Positive Samples:HepG2, Mouse liver
Cellular Location:

Product Images

ApoM Rabbit Monoclonal Antibody (CAB5144)

Western blot - ApoM Rabbit mAb (CAB5144)

Uniprot Information

UniProt Protein Function:APOM: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Plasma protein. Expressed in liver and kidney. Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p21.33

Cellular Component: integral to plasma membrane

Molecular Function:antioxidant activity; lipid transporter activity; phospholipid binding

Biological Process: cholesterol homeostasis; reverse cholesterol transport; response to glucose stimulus; cholesterol efflux; lipoprotein metabolic process

NCBI Summary:The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
UniProt Code:O95445
NCBI GenInfo Identifier:17370872
NCBI Gene ID:55937
NCBI Accession:O95445.2
UniProt Secondary Accession:O95445,Q5SRP4, Q9P046, Q9UMP6, B0UX98,
UniProt Related Accession:O95445
Molecular Weight:188
NCBI Full Name:Apolipoprotein M
NCBI Synonym Full Names:apolipoprotein M
NCBI Official Symbol:APOM 
NCBI Official Synonym Symbols:G3a; NG20; apo-M; HSPC336 
NCBI Protein Information:apolipoprotein M; protein G3a; NG20-like protein; alternative name: G3a, NG20
UniProt Protein Name:Apolipoprotein M
UniProt Synonym Protein Names:Protein G3a
Protein Family:Apomucin
UniProt Gene Name:APOM 
UniProt Entry Name:APOM_HUMAN
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Additional Information

Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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