Description
CEBPZ Transcription Factor Activity Assay
The C/EBPζ Transcription Factor Activity Assay is a reliable and sensitive kit designed for the detection of C/EBPζ transcription factor activity in various biological samples. This kit provides accurate and reproducible results, making it an ideal tool for researchers studying gene regulation and transcription factors.C/EBPζ is a key transcription factor involved in various cellular processes, including immune response, inflammation, and differentiation. Dysregulation of C/EBPζ activity has been implicated in several diseases, making it a promising target for therapeutic interventions.
With its high sensitivity and specificity, the C/EBPζ Transcription Factor Activity Assay is a valuable tool for understanding the molecular mechanisms underlying gene expression and regulation. Researchers can rely on this assay to accurately measure C/EBPζ activity in a variety of sample types, paving the way for new insights into gene transcription and potential therapeutic strategies.
| Product Name: | CEBPZ Transcription Factor Activity Assay |
| Product Code: | TFAB00196 |
| Target: | CEBPZ |
| Synonyms: | CCAAT-box-binding transcription factor, CBF, CCAAT-binding factor |
| Reactivity: | Human |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie CEBPZ transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | C/EBP-zeta: Stimulates transcription from the HSP70 promoter. Belongs to the CBF/MAK21 family. |
| UniProt Protein Details: | Protein type:Transcription factor; RNA-binding Chromosomal Location of Human Ortholog: 2p22.2 Molecular Function:DNA binding Biological Process: positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML). [provided by RefSeq, Jun 2016] |
| UniProt Code: | Q03701 |
| NCBI GenInfo Identifier: | 308153621 |
| NCBI Gene ID: | 10153 |
| NCBI Accession: | Q03701.3 |
| UniProt Secondary Accession: | Q03701,Q8NE75, |
| UniProt Related Accession: | Q03701 |
| Molecular Weight: | 120,974 Da |
| NCBI Full Name: | CCAAT/enhancer-binding protein zeta |
| NCBI Synonym Full Names: | CCAAT/enhancer binding protein zeta |
| NCBI Official Symbol: | CEBPZ |
| NCBI Official Synonym Symbols: | CBF; CBF2; NOC1; HSP-CBF |
| NCBI Protein Information: | CCAAT/enhancer-binding protein zeta |
| UniProt Protein Name: | CCAAT/enhancer-binding protein zeta |
| UniProt Synonym Protein Names: | CCAAT-box-binding transcription factor; CBF; CCAAT-binding factor |
| Protein Family: | CCAAT/enhancer-binding protein |
| UniProt Gene Name: | CEBPZ |
| UniProt Entry Name: | CEBPZ_HUMAN |
