ERF Transcription Factor Activity Assay

SKU:
TFAB00097
€599

Description

ELISA Kit Technical Manual

ERF Transcription Factor activity assay

Product Description:The Assay Genie ERF transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates Assay Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4 °C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

ERF Transcription Factor activity assay Protein Information

UniProt Protein Function:ERF: potent transcriptional repressor that binds to the H1 element of the ETS2 promoter. Belongs to the ETS family of transcription factors. Its function is regulated by phosphorylation.
UniProt Protein Details:

Protein type:DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: cytosol; Golgi apparatus; nucleoplasm; nucleus

Molecular Function:sequence-specific DNA binding; transcription corepressor activity

Biological Process: cell cycle; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent

Disease: Craniosynostosis 4

NCBI Summary:ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
UniProt Code:P50548
NCBI GenInfo Identifier:50403684
NCBI Gene ID:2077
NCBI Accession:P50548.2
UniProt Secondary Accession:P50548,Q59G38, Q9UPI7, B2RAP1, B7Z4R0,
UniProt Related Accession:P50548
Molecular Weight:49,965 Da
NCBI Full Name:ETS domain-containing transcription factor ERF
NCBI Synonym Full Names:ETS2 repressor factor
NCBI Official Symbol:ERF
NCBI Official Synonym Symbols:PE2; CRS4; PE-2
NCBI Protein Information:ETS domain-containing transcription factor ERF
UniProt Protein Name:ETS domain-containing transcription factor ERF
UniProt Synonym Protein Names:Ets2 repressor factor; PE-2
Protein Family:Essential recombination function protein
UniProt Gene Name:ERF
UniProt Entry Name:ERF_HUMAN
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Additional Information

Product Type:
ELISA
ELISA Type:
Transcription Factor Assay
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