Description
FOXL1 Transcription Factor Activity Assay
The FOXL1 Transcription Factor Activity Assay Kit is a powerful tool for measuring the activity of FOXL1, a key transcription factor involved in regulating gene expression. This kit is designed for use in both research and clinical settings, providing accurate and reliable results in a variety of sample types.FOXL1 plays a critical role in various biological processes, including cell differentiation, development, and disease progression. By measuring FOXL1 activity, researchers can gain valuable insights into the underlying mechanisms of diseases such as cancer, autoimmune disorders, and neurodegenerative conditions.
With its high sensitivity and specificity, the FOXL1 Transcription Factor Activity Assay Kit offers researchers a convenient and efficient way to study FOXL1 function and its impact on gene regulation. Whether you are studying basic biology or searching for potential therapeutic targets, this kit is an essential tool for advancing your research.
| Product Name: | FOXL1 Transcription Factor Activity Assay |
| Product Code: | TFAB00111 |
| Target: | FOXL1 |
| Synonyms: | Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC-7 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie FOXL1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | FOXL1: Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 16q24 Cellular Component: nucleus Molecular Function:DNA binding; sequence-specific DNA binding; DNA bending activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; organ morphogenesis; heart development; proteoglycan biosynthetic process; multicellular organismal development; regulation of Wnt receptor signaling pathway; visceral mesoderm-endoderm interaction involved in midgut development |
| NCBI Summary: | This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q12952 |
| NCBI GenInfo Identifier: | 13638268 |
| NCBI Gene ID: | 2300 |
| NCBI Accession: | Q12952.2 |
| UniProt Secondary Accession: | Q12952,Q17RR1, Q9H242, |
| UniProt Related Accession: | Q12952 |
| Molecular Weight: | 345 |
| NCBI Full Name: | Forkhead box protein L1 |
| NCBI Synonym Full Names: | forkhead box L1 |
| NCBI Official Symbol: | FOXL1 |
| NCBI Official Synonym Symbols: | FKH6; FKHL11; FREAC7 |
| NCBI Protein Information: | forkhead box protein L1; forkhead-like 11; forkhead-related protein FKHL11; forkhead-related transcription factor 7 |
| UniProt Protein Name: | Forkhead box protein L1 |
| UniProt Synonym Protein Names: | Forkhead-related protein FKHL11; Forkhead-related transcription factor 7; FREAC-7 |
| Protein Family: | Forkhead box protein |
| UniProt Gene Name: | FOXL1 |
| UniProt Entry Name: | FOXL1_HUMAN |
