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Anti-GLUT3 Antibody (CAB4137)

SKU:
CAB4137
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction
$167 - $503
Frequently bought together:

Description

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Antibody Name:Anti-GLUT3 Antibody
Antibody SKU:CAB4137
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human GLUT3
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, Jurkat, SH-SY5Y, Mouse testis, Mouse brain, Rat testis, Rat brain
Immunogen:A synthesized peptide derived from human GLUT3
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6515
Uniprot:P11169
Cellular Location:
Calculated MW:54kDa
Observed MW:48-60KDa
Synonyms:GLUT3
Background:
UniProt Protein Function:GLUT3: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. It???s surface expression is induced by insulin. It is restricted in humans to brain, testis (in the spermatozoa), and skeletal muscle, mostly in triads of slow-twitch fibres. Detected only in the brain of mouse and rat. IHC demonstrates its present in neurons, mainly at the plasma membrane, and to a lesser extent on intracellular vesicles distinct from synaptic vesicles. Present in the a-granules of human platelets, where it is translocated to the cell surface in response to thrombin stimulation. Its surface expression is increased by insulin or insulin growth-factor in cultured L6 muscle cells.
UniProt Protein Details:

Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function:D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; glucose binding; glucose transmembrane transporter activity

Biological Process: glucose transport; L-ascorbic acid metabolic process

UniProt Code:P11169
NCBI GenInfo Identifier:121760
NCBI Gene ID:6515
NCBI Accession:P11169.1
UniProt Secondary Accession:P11169,Q6I9U2, Q9UG15, B2R606, D3DUU6,
UniProt Related Accession:P11169
Molecular Weight:53924 Da
NCBI Full Name:Solute carrier family 2, facilitated glucose transporter member 3
NCBI Synonym Full Names:solute carrier family 2 member 3
NCBI Official Symbol:SLC2A3  
NCBI Official Synonym Symbols:GLUT3  
NCBI Protein Information:solute carrier family 2, facilitated glucose transporter member 3
UniProt Protein Name:Solute carrier family 2, facilitated glucose transporter member 3
UniProt Synonym Protein Names:Glucose transporter type 3, brain; GLUT-3
Protein Family:Solute carrier family
UniProt Gene Name:SLC2A3  
UniProt Entry Name:GTR3_HUMAN
Anti-GLUT3 Antibody (CAB4137)Western blot - GLUT3 Rabbit mAb (CAB4137)

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